Asian Pacific Journal of Nursing and Health Sciences

Sickle Cell Disease - A Case Report

Samarpita Pramanik, R.N. R.M. MSc (N) — Fri, 31 Dec 2021 00:00:00 +0000

Sickle cell disease (SCD) is a major healthcare and societal problem affecting millions of people worldwide. In United States of America (USA), it is the most common genetic disorder affecting more than 80,000 people per year; majority of which are the African Americans Arabian and Indian. It is a genetic blood disorder affecting the red blood cells. Sickle cell pain is the hallmark of sickle cell disease and is associated with a very high mortality and morbidity rates. Being a genetic abnormality, the complete eradication of the disease from the affected seems to be difficult. Genetic counselling during pregnancy being the prime preventive step, Hematopoietic stem cell transplantation becomes the mainstay of treatment for complete eradication of the disease. But it is not done very often because of the significant risks involved.

Impact of Mobile Phone Use on Various Dimensions of Health among Students During COVID-19

Ramkumar Garg, Bhartendra Sharma, Prabha Garg — Fri, 31 Dec 2021 00:00:00 +0000

Although, all the countries have used various measures to reduce the transmission of the COVID-19 like complete or partial lockdown, travel restrictions, social restrictions etc but the effectiveness of these measures completely depend on the cooperation of the society members. The knowledge, attitudes and practices of people toward any disease play a vital role in determining a community’s readiness to accept behavioural change measures from government authorities. The aim of this study was to determine the Impact of Mobile Phone Use on Various Dimensions among students during COVID-19 of India. A cross-sectional online survey was conducted between 20^th May and 05^thJune 2020. 670 completed survey were received. The data was collected by following questionnaires: demographic characteristics questionnaire, knowledge questionnaire. Descriptive & inferential statistics were used to analyse the data. The study result revealed that the students have more negative impacts (52.22%) than positive impacts (47.78%) & significance association was found with education of students (p>0.05).

FDA-Approved Natural Disintrgrant for Fast Dissolving Tablets

Ujjwal Nautyal, Rajat Katna, Deepak Kumar — Fri, 31 Dec 2021 00:00:00 +0000

Orally disintegrating tablets (ODTs) are an emerging trend in novel drug delivery system and have received ever-increasing demand during the last few decades. ODTs are solid unit dosage forms, which disintegrates or dissolves rapidly in the mouth without chewing and water. This type of property in dosage form can be attained by addition of different excipients, in which disintegrants are the key adjuvant. In recent years, several newer agents have been developed known as super-disintegrants. Super-disintegrants are used to improve the efficacy of solid dosage form and influence the release rate of dosage form. Diverse categories of super-disintegrants are such as synthetic, semi-synthetic, natural and co-processed blends etc. These have been employed to develop effectual ODTs and to overcome the limitations of conventional tablet dosage forms. The plant derived natural super disintegrants comply with many requirements of pharmaceutical excipients as they are non-toxic, stable, easily available, associated with less regulatory issues as compared to their synthetic counterpart and inexpensive; also these can be easily modified into more polar form. This review discuss about the development of various kind of natural super-disintegrating agents, along with their role in the tablet disintegration and as potent candidate to be used in ODTs, which are being used in the formulation to provide the safer, effective drug delivery with patient compliance.

Development and Evaluation of Interpenetrating Polymer Network Hydrogel for Controlled Release of Cefadroxil

Chandra Kumar, Yogendra Singh, G Jeyabalan — Fri, 31 Dec 2021 00:00:00 +0000

Oral drug delivery is the most widely utilized route of administration among all the routes that have been explored for systemic delivery of drugs via pharmaceutical products of different dosage form. By increasing the concentration of cross linking agent drug entrapment efficiency increase but in case of percentage yield firstly it increases (A9- A10) after that in it decrease. Out of all the twelve formulation A-10 formulation is optimized and taken for further characterization.

Phytoconstituents and Formulations For Wound Healing: A Review

Tamana Bhardwaj, Yusra Ahmad, Vipin Kumar — Fri, 31 Dec 2021 00:00:00 +0000

Use of herbal drugs to treat disease is almost universal and more affordable as there is widespread availability of herbs in the Himalayas. Number of aspects are associated with applications of herbal medicines in wound healing. With proper identification, phytochemical screening and performing toxicological studies, herbal medicine possesses various advantages like reduced side effects, effective with chronic conditions, cost effective, widespread availability. Besides these, it can be made a promising novel medicine with the use of Targeted drug delivery system.In view of this a detailed review of literature was carried out on different formulations and phytoconstituents responsible for wound healing activity, with special emphasis on different stages of wound healing, which could be of prodigious help in managing and treating various types of wounds.