A Mini Review on dutasteride

Abstract

Dihydrotestosterone (DHT) is the main hormone responsible for the gradual hair loss disorder known as androgenetic alopecia (AGA). Despite being a strong dual inhibitor of 5-alpha-reductase (5-AR), oral dutasteride's systemic use is restricted due to possible adverse effects like sexual dysfunction. The formulation and assessment of topical dutasteride are examined in this review, with an emphasis on cutting-edge delivery methods such as niosomal and nanoemul gels. We examine the medicine's chemical makeup, preparation techniques, and assessment metrics including drug release and particle size. The potential of topical dutasteride as a targeted, safer alternative for hair restoration is highlighted by discussing current research gaps and future treatment prospects